Annotation: The experience of medicine and biology has been studied, as regards anticipatory actions against viruses and infections. An analogy of the approaches to fighting zero-day attacks in cyber systems and approaches to fighting "illnesses of dirty hands" in medicine was established. The experience of epidemiology was extended to the fight against threats of "zero day" in cybernetic attacks. The use of cluster analysis in various fields of human activity was analyzed. The taxonometric method was chosen for the tasks of identifying cybernetic threats. The taxonometric method allows the creation of benchmarks in the absence of prior information on new types of threats. Taking into account the specificity of the tasks of cybernetic security, the taxonometric method and criteria for determining the etalon objects were improved. The possibility of implementing the proposed approach was tested experimentally on ordinary budget personal computers.