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  5. Development of diagnostic sensors based on the regulatory mechanism of biosystems and their reactivity

Development of diagnostic sensors based on the regulatory mechanism of biosystems and their reactivity

I. Ogorodnyk, O. Vуsotska, M. Ternyuk
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Description: It is known that the human body is an open information biosystem. This means that everything that happens in the person’s environment and what he touches is instantly fixed by the limbic system and displayed on the state of the autonomic nervous system, on which the skin resistance depends. Arises a so-called sympathetic skin response (SSR). This is due to the openness of biosystems and, in connection with this, the relative instability of their state, which is necessary to maintain a balance of internal entropy and homeostasis. The influence of external information on the body can be estimated through a change in the entropy of the state. The more this influence increases or decreases internal entropy, the greater the sympathetic skin reaction. Such reactivity makes it possible to use binary testing to determine existing dysfunctions or destructive processes in the human body. The article reviews the theoretical background and practical application of non-invasive diagnostic methods based on the measurement of biosignals and the impedance of biological tissues. The prospects of design and developing reliable methods for screening biosystems and the introduction of remote monitoring of the human body are shown. Also considered are the features of creating a multi-contact biosensor for measuring skin impedance in a non-invasive diagnostic system, which is based on binary identification of the state of the human body. The biosensor provides the receipt and primary processing of information that appears during the reactivity of a biosystem to the action of information markers. Creating a biosensor will eliminate subjectivity in testing and the need for extensive operator experience. This will make it possible to standardize the method for use in a wide range of medical specialists.

Keywords: biological object, impedance, biosensor, binary identification, non-invasive diagnostics


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