Annotation: Among external factors, the greatest influence on the dynamics of the flight has wind. It has both a chaotic turbulent component and a constant component, which may not change throughout the flight. The average speed of a constant wind component has a practically horizontal direction and significantly influences the solving of the navigational tasks. The wind speed can be taken into account as a result of the unmanned aerial vehicle (UAV) flight route planning. In recent studies and publications the wind influence was not taken into consideration when solving trajectory problems of the UAV flight. The basic calculated relations and optimization approaches of the flight program of an UAV on the route in wind conditions are determined. It is proposed to use the simplest algorithm of complete overview, when finding the best UAV flight route, where the number of route points does not exceed 20. This algorithm guarantees the exact solution finding. According to the research results, the influence of the continuous wind on the route optimality (optimal sequence of the route points passage) was not registered. The presence of the wind considerably affects the UAV overall flight time on the route.